Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal
Abstract
We reappraise the psychiatric potential of calcium channel blockers (CCBs).
First, voltage-gated calcium channels are risk genes for several disorders.
Second, use of CCBs is associated with altered psychiatric risks and outcomes.
Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications.
Citations
Paul J. Harrison, Elizabeth M. Tunbridge, Annette C. Dolphin, Jeremy Hall. Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal. The British Journal of Psychiatry, 1-4 24 June 2019
Sponsorship: Supported by the NIHR
Page last reviewed: 12 June, 2025
Metadata
Author(s): Harrison, Paul J; Tunbridge, Elizabeth
Collection: 123456789/13
Subject(s): Bipolar Disorder
Format(s): Article
Date issued: 2019-06
ISSN: 1472-1465
ID: 227